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[DOI] [PMC free article] [PubMed] [Google Scholar] 47.Napolitano G., Fasciolo G., Venditti P
Exactly what is it
[7] It should not be used in individuals with hormone-sensitive tumors, such as prostate cancer or breast cancer, due to the risk of stimulating tumor growth through increased androgen or estrogen production
MGFs distinguishing feature is its unique C-terminal E-peptide (the Ec extension), which has been studied for potential IGF-1R-independent actions on muscle satellite cell activation and proliferation, separate from the mature IGF-1 domains receptor signaling
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